155894-96-5 Usage
General Description
(+)-N-TRIFLUOROACETYL-L-PHENYLGLYCINE is a chemical compound with the formula C11H10F3NO3. It is a derivative of phenylglycine, an amino acid, and has a trifluoroacetyl group attached to the nitrogen atom. (+)-N-TRIFLUOROACETYL-L-PHENYLGLYCINE is commonly used as a chiral building block in organic synthesis and pharmaceutical research. It is known for its ability to act as a versatile intermediate in the production of various pharmaceutical drugs. The trifluoroacetyl group provides a unique reactivity that allows for the modification of the compound's chemical properties, making it particularly valuable in the development of new drug candidates. Additionally, (+)-N-TRIFLUOROACETYL-L-PHENYLGLYCINE is often used in the synthesis of peptides and peptides mimics due to its selective reactivity and ability to introduce chirality.
Check Digit Verification of cas no
The CAS Registry Mumber 155894-96-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,8,9 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 155894-96:
(8*1)+(7*5)+(6*5)+(5*8)+(4*9)+(3*4)+(2*9)+(1*6)=185
185 % 10 = 5
So 155894-96-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H8F3NO3/c11-10(12,13)9(17)14-7(8(15)16)6-4-2-1-3-5-6/h1-5,7H,(H,14,17)(H,15,16)/t7-/m0/s1
155894-96-5Relevant articles and documents
Trifluoroacetylation of amino acids under aqueous conditions using a readily prepared non-odoriferous reagent
Hickey, Matthew R.,Nelson, Todd D.,Secord, Elizabeth A.,Allwein, Shawn P.,Kress, Michael H.
, p. 255 - 258 (2005)
The synthesis of S-dodecyltrifluorothioacetate and its application to trifluoroacetylation of amino acids under aqueous conditions are described. This reagent afforded good isolated yields (71-92%) of the N-trifluoroacetyl derivatives via an operationally simple and odor free procedure.
Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors
Di Santo, Roberto,Costi, Roberta,Roux, Alessandra,Artico, Marino,Befani, Olivia,Meninno, Tiziana,Agostinelli, Enzo,Palmegiani, Paola,Turini, Paola,Cirilli, Roberto,Ferretti, Rosella,Gallinella, Bruno,La Torre, Francesco
, p. 4220 - 4223 (2007/10/03)
Pyrrolylethanoneamines 1-12, 18-23 and related amino alcohols 13-15, 24-27 were synthesized and tested against monoamine oxidases A and B (MAO-A and MAO-B) enzymes. In general, aminoketones 1-12, 18-23 were found to be potent and selective MAO-A inhibitor
