155897-13-5

Upstream product

• 100-73-2 acrolein dimer 
• 155795-48-5 (diethoxyphosphoryl)acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl ester 
• 113368-90-4 (Diisopropoxy-phosphoryl)-acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 155795-46-3 [bis(2,2,2-trifluoroethoxy)phosphoryl]acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl ester 

Downstream Products

• 837428-39-4 10-benzyl 1-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl] (2E,4R,8E)-4-[(diphenylphosphoryl)oxy]deca-2,8-dienedioate 
• 837428-43-0 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (4R,10R)-10-hydroxy-12-(trimethylsilyl)-4-[2-(trimethylsilyl)ethoxy]dodec-11-ynoate 
• 837428-24-7 10-benzyl 1-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl] (2E,4R,8E)-4-[2-(trimethylsilyl)ethoxy]deca-2,8-dienedioate 
• 837428-41-8 (4R)-4-[2-(trimethylsilyl)ethoxy]decanedioic acid 1-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl] ester 
• 837428-47-4 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (4R)-10-hydroxy-4-[2-(trimethylsilyl)ethoxy]decanoate 
• 837428-42-9 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (4R)-10-oxo-4-[2-(trimethylsilyl)ethoxy]decanoate 
• 837428-37-2 10-benzyl 1-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl] (2E,4R,8E)-4-hydroxydeca-2,8-dienedioate 

Relevant academic research and scientific papers

Total synthesis of pyranicin

(Chemical Equation Presented) A stereocontrolled convergent synthesis of the annonaceous acetogenin pyranicin (1) is presented. Asymmetric Horner-Wadsworth-Emmons (HWE) reactions were used to access key intermediates. The tetrahydropyran derivative 2 was

Parallel kinetic resolution of racemic aldehydes by use of asymmetric Horner-Wadsworth-Emmons reactions

(Formula presented) A racemic aldehyde can undergo parallel kinetic resolution (PKR) by simultaneous reaction with two different chiral phosphonates, differing either in the structure of the chiral auxiliary or in the structure of the phosphoryl group (i.