155926-82-2Relevant articles and documents
Preparation and characterization of phase-segregated vesicles of photopolymerizable diacetylene mixed with nonpolymerizable amphiphiles
Matsumoto, Jin,Yoneda, Koshiro,Tasaka, Jun,Shiragami, Tsutomu,Yasuda, Masahide
, p. 1551 - 1557 (2010)
A mixture of sodium 1,2-di(hexadecyloxycarbonyl)ethanesulfonate (2C16S) with photopolymerizable 1,2-di(10,12- tricosadiynoyl)-sn-glycerol 3-phosphocholine (DTPC) in a 2:100 ratio was treated by modified thin-film hydration to give an aggregate which became polymerized giant vesicles (GVs) under irradiation at 254 nm. The autofluorescence of the GVs was analyzed with a confocal laser scanning microscope at the cross section, revealing a 3.8-μm diameter ring shape and the presence of a dark part of ca. 1 μm in the ring. When octadecylrhodamine B (RhB) as an amphiphilic fluorescence probe was added to the GV, the fluorescence of RhB was emitted from the whole ring. Therefore, phase segregation of 2C16S from DTPC was confirmed. Similarly, mixed vesicles of N,N-di(2-hexadecanoyloxyethyl)dimethylammonium iodide with DTPC were found to be 3.7-μm diameter phase-segregated vesicles with a dark portion of ca. 1 μm on the ring in the cross sectional image. On the other hand, DTPC vesicles mixed with 1,2-di(dodecyloxycarbonyl)ethanesulfonate, N,N-di(2- dodecanoyloxyethyl)dimethylammonium iodide, and N,N-di(2-tetradecanoyloxyethyl) dimethylammonium iodide formed sphere structures filling the inside of the vesicles. The segregation mechanism was explained by the difference in the main phase transition temperature of each amphiphile.
