155940-98-0Relevant articles and documents
Palladacycle-catalyzed phosphonation of aryl halides in neat water
Xu, Kai,Yang, Fan,Zhang, Guodong,Wu, Yangjie
supporting information, p. 1055 - 1060 (2013/07/26)
An efficient and generally applicable protocol for the palladacycle- catalyzed arylation of diisopropyl H-phosphonate in water was developed. The remarkable features of this C-P bond-forming reaction include wide substrate scope including the inactive electron-rich and electron-neutral aryl chlorides, the weak inorganic base KF instead of strong bases such as KOtBu or NaOtBu for the activation of C-Cl bond, and the addition of isopropanol to avoid the decomposition of diisopropyl H-phosphonate.