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Ethyl 3,4-dihydro-4-oxoquinazoline-6-carboxylate, commonly known as methotrexate, is a potent and extensively utilized medication primarily for the treatment of cancer and autoimmune diseases. It functions by inhibiting the enzyme dihydrofolate reductase, which plays a crucial role in the synthesis of DNA, RNA, and proteins. This action hampers the proliferation of cancer cells and mitigates the immune response in autoimmune conditions. Methotrexate is administered orally or through injection and possesses both anti-inflammatory and immunosuppressive properties. It is a highly regulated and potent drug that necessitates careful monitoring by healthcare professionals due to its potential for significant side effects.

155960-91-1

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155960-91-1 Usage

Uses

Used in Oncology:
Ethyl 3,4-dihydro-4-oxoquinazoline-6-carboxylate is used as an anticancer agent for the treatment of various malignancies. It targets the dihydrofolate reductase enzyme, thereby disrupting the synthesis of essential cellular components and inhibiting the growth of cancer cells.
Used in Autoimmune Disease Treatment:
Ethyl 3,4-dihydro-4-oxoquinazoline-6-carboxylate is used as a disease-modifying antirheumatic drug (DMARD) for the management of autoimmune conditions such as rheumatoid arthritis, psoriasis, and lupus. It exhibits immunosuppressive and anti-inflammatory properties, helping to control the immune response and alleviate symptoms.
Used in Drug Formulation:
Ethyl 3,4-dihydro-4-oxoquinazoline-6-carboxylate is used as an active pharmaceutical ingredient in various drug formulations, including tablets, injections, and other dosage forms, to ensure effective delivery and therapeutic efficacy in treating cancer and autoimmune diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 155960-91-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,9,6 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 155960-91:
(8*1)+(7*5)+(6*5)+(5*9)+(4*6)+(3*0)+(2*9)+(1*1)=161
161 % 10 = 1
So 155960-91-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H10N2O3/c1-2-16-11(15)7-3-4-9-8(5-7)10(14)13-6-12-9/h3-6H,2H2,1H3,(H,12,13,14)

155960-91-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 3,4-dihydro-4-oxoquinazoline-6-carboxylate

1.2 Other means of identification

Product number -
Other names Ethyl 4-oxo-3,4-dihydroquinazoline-6-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:155960-91-1 SDS

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