155975-27-2Relevant academic research and scientific papers
Hydroxy-directed Ketone Reduction. Application to the Synthesis of (+)-8,8a-Diepicastanospermine
Thompson, Stephen H. J.,Subramanian, R. Sankara,Roberts, John K.,Hadley, Michael S.,Gallagher, Timothy
, p. 933 - 934 (1994)
Reduction of heterocyclic-derived aldol adducts 2 and 3 using NaBH(OAc)3 is stereoselective and proceeds via a hydroxy-directed mechanism to give 6 and 7, respectively, thereby complementing the stereoselectivity available with NaBH4; a synthesis of (+)-8
