155997-96-9Relevant academic research and scientific papers
Protecting group for carboxyl function: Mild and facile cleavage of 2- cyanoethyl ester under non-hydrolytic conditions
Kita,Maeda,Takahashi,Fukui,Ogawa,Hatayama
, p. 147 - 150 (2007/10/02)
The use of the 2-cyanoethyl group for carboxyl-protection is described. This group was readily introduced by esterification using ethylene cyanohydrin and the deprotection was carried out under mild conditions using tetrabutylammonium fluoride in dimethylformamide-tetrahydrofuran.
