156006-28-9

Basic information

• Product Name: 3 4 5-TRIFLUOROPHENYLMAGNESIUM BROMIDE
• Synonyms: 3,4,5-Trifluorophenylmagnesium bromide, 0.3M solution in THF, AcroSeal;3,4,5-TrifluorophenylMagnesiuM broMide, 0.50 M in 2-MeTHF;3,4,5-TrifluorophenylMagnesiuM broMide, 0.3 M solution in THF, SpcSeal;3,4,5-Trifluoro-1-bromomagnesiumbenzene;magnesium,1,2,3-trifluorobenzene-5-ide,bromide;3,4,5-trifluorophenylmagnesium bromide solution;3,4,5-Trifluorophenylmagnesium bromide solution 0.3 in THF
• CAS NO: 156006-28-9
• Molecular Formula: C₆H₂BrF₃Mg
• Molecular Weight: 235.28
• Product Categories: Grignard Reagent;Aryl;Grignard Reagents;Organometallic Reagents
• Mol File: 156006-28-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 65 °C
• Flash Point: 1 °F
• Appearance: /
• Density: 0.975 g/mL at 25 °C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3 4 5-TRIFLUOROPHENYLMAGNESIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3 4 5-TRIFLUOROPHENYLMAGNESIUM BROMIDE(156006-28-9)
• EPA Substance Registry System: 3 4 5-TRIFLUOROPHENYLMAGNESIUM BROMIDE(156006-28-9)

Safety Data

• Hazard Codes: F,C,Xn
• Statements: 11-14-19-34-40-36/37/38
• Safety Statements: 16-26-36/37/39-45-36/37
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 156006-28-9(Hazardous Substances Data)

Usage

General Description

3 4 5-Trifluorophenylmagnesium bromide is a chemical compound used in organic synthesis as a source of the 3,4,5-trifluorophenyl group. It is a highly reactive and versatile reagent that is commonly utilized in Grignard reactions to introduce the trifluoromethyl group into various organic compounds. This reagent is also commonly used in pharmaceutical and agrochemical research and development, as well as in the synthesis of fine chemicals and materials. Due to its high reactivity, 3 4 5-Trifluorophenylmagnesium bromide is often handled and stored under strict air-free and moisture-free conditions to prevent unintended reactions. Overall, this compound is a valuable tool in the field of organic synthesis, particularly for the introduction of the trifluoromethyl group into complex molecules.

InChI:InChI=1/C6H2F3.BrH.Mg/c7-4-2-1-3-5(8)6(4)9;;/h2-3H;1H;/q;;+1/p-1/rC6H2BrF3Mg/c7-11-3-1-4(8)6(10)5(9)2-3/h1-2H

Upstream product

• 7439-95-4 magnesium 
• 138526-69-9 3,4,5-trifluoro-1-bromobenzene 

Downstream Products

• 937813-35-9 1-(4-bromobutyryl)-2-(3,4,5-trifluorophenyl)-2,3-dihydro-1H-pyridin-4-one 
• 238743-47-0 ethyl 2-(3,4,5-trifluorophenyl)acetate 
• 1267635-99-3 1,2-bis[di(3,4,5-trifluorophenyl)phosphino]benzene 
• 266687-18-7 5-cyclohexyl-1,2,3-trifluorobenzene 
• 263243-17-0 3,4,5-trifluorophenyldifluoroborane 

Relevant articles and documents

SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS

Compounds of the general formula:processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

Method for Producing 2-aminobiphenylene

The present invention relates to a process for preparing 2-aminobiphenyls of the formula I in which n is 0, 1, 2 or 3,R1 is hydrogen, cyano or fluorine, andeach R2 is independently selected from cyano, fluorine, C1-C4

TWO CYCLIC OXOMORPHORIN DERIVATIVES

The present invention relates to a compound represented by formula (I): wherein R1 represents a C1-3 alkyl group, R2 represents a hydrogen atom or a C1-3 alkyl group, Ar represents a phenyl group or the like which may be substituted with 1 to 3 substituents, X represents an oxygen atom or the like, n and m are the same or different and integers of 0 to 2, or a pharmacologically acceptable salt, and use thereof as a medicament.