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15603-27-1

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15603-27-1Related news

Effect of Cisplatin (cas 15603-27-1) on pancreas and testies in Wistar rats: biochemical parameters and histology09/03/2019

ObjectiveTo investigate effect of cisplatin on biochemical parameter and histology of pancreas and testis in Wistar rats.detailed

Oridonin elevates sensitivity of ovarian carcinoma cells to Cisplatin (cas 15603-27-1) via suppressing Cisplatin (cas 15603-27-1)-mediated autophagy09/02/2019

BackgroundCisplatin resistance has been found to contribute to the failure of ovarian carcinoma treatment. Oridonin is a natural en-kaurane tetracyclic diterpenoid compound discovered in Rabdosia rubescene (Henmsl.) Hara. Herein, we tested whether oridonin could exert chemo-sensitization activit...detailed

Novel α,β-unsaturated hydroxamic acid derivatives overcome Cisplatin (cas 15603-27-1) resistance09/01/2019

A series of α,β-unsaturated hydroxamic acid derivatives as novel HDAC inhibitors (HDACi) with structural modifications of the connecting unit and the CAP group was synthesized. The in vitro evaluation against the human cancer cell lines A2780 and Cal27 identified 6e and 7j as the most potent c...detailed

Targeting STAT3 inhibition to reverse Cisplatin (cas 15603-27-1) resistance08/31/2019

Cisplatin is one of the most frequently used chemotherapeutic agents for treatment of a wide range of cancer types. Nevertheless, the intrinsic or acquired resistance to cisplatin remains a major obstacle for cancer therapy. There are a number of factors contributing to the onset of this phenoty...detailed

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