156050-38-3Relevant academic research and scientific papers
A Practical Access to Functionalized Alkyl Sulfinates
Tran,Flamme,Chagnes,Haddad,Phansavath,Ratovelomanana-Vidal
, p. 1622 - 1626 (2018/06/12)
We describe herein a three-step synthesis of aliphatic sulfinates. This cost-effective method involves the use of 2-mercaptobenzothiazole under mild conditions and exhibits good yields (up to 78% over three steps). This approach provides an access to a wi
A Protocol to Transform Sulfones into Nitrones and Aldehydes
Rodrigo, Eduardo,Alonso, Inés,Cid, M. Belén
supporting information, p. 5789 - 5793 (2018/09/29)
A simple method to transform sulfones into nitrones and therefore into the corresponding carbonyl derivatives has been developed. Some examples demonstrate that it is a new reliable and versatile reaction in the toolbox of sulfones that has great synthetic potential. NMR and computational studies were used to elucidate the mechanism.
A Protocol to Transform Sulfones into Nitrones and Aldehydes
Rodrigo, Eduardo,Alonso, Inés,Cid, M. Belén
supporting information, (2018/09/27)
A simple method to transform sulfones into nitrones and therefore into the corresponding carbonyl derivatives has been developed. Some examples demonstrate that it is a new reliable and versatile reaction in the toolbox of sulfones that has great synthetic potential. NMR and computational studies were used to elucidate the mechanism.
Total synthesis of (-)-blepharocalyxin D
Ko, Haye Min,Lee, Dong Gil,Kim, Min Ah,Kim, Hak Joong,Park, Jaejoon,Lah, Myoung Soo,Lee, Eun
, p. 141 - 144 (2007/10/03)
The Prins cyclization strategy was successfully applied in the total synthesis of (-)-blepharocalyxin D, a cytotoxic dimeric diarylheptanoid isolated from Alpinia blepharocalyx.
Stereoselective synthesis of (-)-blepharocalyxin D
Ko, Haye Min,Lee, Dong Gil,Kim, Min Ah,Kim, Hak Joong,Park, Jaejoon,Lah, Myoung Soo,Lee, Eun
, p. 5797 - 5805 (2008/02/03)
The Prins cyclization strategy was successfully applied in the stereoselective synthesis of (-)-blepharocalyxin D (1), a cytotoxic dimeric diarylheptanoid isolated from Alpinia blepharocalyx.
Stereochemistry of direct olefin formation from carbonyl compounds and lithiated heterocyclic sulfones
Baudin, J. B.,Hareau, G.,Julia, S. A.,Lorne, R.,Ruel, O.
, p. 856 - 878 (2007/10/02)
The conditions for the title reaction were studied for the 2-benzothiazole and 2-pyridine series and for some examples in the 2-pyrimidine series.The olefin preparations were generally observed to be more efficient for 2-BT-sulfone systems.From the data of the hundred cases studied, it can be concluded that (E)-olefins are obtained: (i) from saturated BT-sulfones and aromatic aldehydes; and (ii) from benzylic BT-sulfones and branched saturated aldehydes (isobutyraldehyde, pivalaldehyde) or α,β-ethylenic or aromatic aldehydes. (Z)-olefins arise: (i) fom propargylic BT-sulfones and saturated or aromatic aldehydes; and (ii) from allylic or benzylic Pyr-sulfones and saturated aldehydes.Possible mechanisms for this new olefination procedure were examined. - heteroaromatic sulfones, organolithium derivatives, intramolecular ipso reactions, stereochemistry, elimination, olefination.
