156054-91-0Relevant articles and documents
Synthesis of Isobenzofuran Derivatives as Heterocyclic Analogues of the Herbicide Sindone B
Stanetty, Peter,Rodler, Inge K.,Krumpak, Barbara
, p. 333 - 339 (1994)
The target compounds 21-27 were synthesized via bromination of the N,N,1,1-tetramethylisobenzofuranamines 13, 15 and 16, subsequent bromine-lithium exchange and reaction with propanal or propanoyl chloride, respectively.In the course of some model reactions undertaken to test a synthetic strategy based on directed ortho-lithiation governed by the dimethylamino-group a useful synthesis of the ketone 3 was developed.
