156059-09-5 Usage
General Description
"(R,S)-FMOC-ALPHA-METHOXYGLYCINE" is a type of chiral molecule used commonly in chemical research. Being a part of the Fmoc protected amino acids family, it plays a crucial role in solid-phase peptide synthesis (SPPS) methodology. Its Fmoc (Fluorenylmethyloxycarbonyl) group is particularly useful in peptide synthesis due to its easy removal under mild basic conditions, leaving the peptide chain undamaged. In addition to its practical applications in chemical and pharmaceutical research, this compound features an appealing set of properties - its chirality (R,S configuration) enables it to exist in two enantiomeric forms, while its methoxy and glycine functionalities add elements of versatility and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 156059-09-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,0,5 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 156059-09:
(8*1)+(7*5)+(6*6)+(5*0)+(4*5)+(3*9)+(2*0)+(1*9)=135
135 % 10 = 5
So 156059-09-5 is a valid CAS Registry Number.
156059-09-5Relevant articles and documents
Solid phase synthesis of α-hydroxyglycine extended peptides -biological precursors of peptide amides
Brown, Angus R.,Ramage, Robert
, p. 789 - 792 (1994)
Fmoc α-methoxyglycine can be incorporated into solid phase peptide synthesis (SPPS) methodology to give α-hydroxyglycine extended peptides on final deprotection and cleavage from the solid support with trifluoroacetic acid containing 5% H2O.
