156079-37-7

Basic information

• Product Name: Carbonic acid 4-[bis-(2-chloro-ethyl)-amino]-3-isopropyl-phenyl ester 4-nitro-phenyl ester
• Synonyms: Carbonic acid 4-[bis-(2-chloro-ethyl)-amino]-3-isopropyl-phenyl ester 4-nitro-phenyl ester
• CAS NO: 156079-37-7
• Molecular Weight: 441.311
• Mol File: 156079-37-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbonic acid 4-[bis-(2-chloro-ethyl)-amino]-3-isopropyl-phenyl ester 4-nitro-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbonic acid 4-[bis-(2-chloro-ethyl)-amino]-3-isopropyl-phenyl ester 4-nitro-phenyl ester(156079-37-7)
• EPA Substance Registry System: Carbonic acid 4-[bis-(2-chloro-ethyl)-amino]-3-isopropyl-phenyl ester 4-nitro-phenyl ester(156079-37-7)

Safety Data

• Hazardous Substances Data: 156079-37-7(Hazardous Substances Data)

Upstream product

• 82774-61-6 3-(1-methylethyl)-4-aminophenol 
• 156079-09-3 4-[Bis-(2-hydroxy-ethyl)-amino]-3-isopropyl-phenol 
• 156079-22-0 (4-Benzyloxy-2-isopropyl-phenyl)-bis-(2-chloro-ethyl)-amine 
• 156079-16-2 2-[(4-Benzyloxy-2-isopropyl-phenyl)-(2-hydroxy-ethyl)-amino]-ethanol 

Downstream Products

• 156079-02-6 (S)-2-{4-[Bis-(2-chloro-ethyl)-amino]-3-isopropyl-phenoxycarbonylamino}-pentanedioic acid 
• 172974-09-3 (S)-2-{4-[Bis-(2-chloro-ethyl)-amino]-3-isopropyl-phenoxycarbonylamino}-pentanedioic acid dibenzyl ester 

Relevant articles and documents

Optimization of Alkylating Agent Prodrugs Derived from Phenol and Aniline Mustards: A New Clinical Candidate Prodrug (ZD2767) for Antibody-Directed Enzyme Prodrug Therapy (ADEPT)

Sixteen novel potential prodrugs derived from phenol or aniline mustards and their 16 corresponding drugs with ring substitution and/or different alkylating functionalities were designed.The 4-bis(2-bromoethyl)-(1a), 4-bis(2-iodoethyl)-(1b), and