156101-10-9Relevant academic research and scientific papers
Erinacines A, B and C, strong stimulators of nerve growth factor (NGF)-synthesis, from the mycelia of Hericium erinaceum
Kawagishi, Hirokazu,Shimada, Atsushi,Shirai, Ryoko,Okamoto, Kenji,Ojima, Fumihiro,Sakamoto, Hideki,Ishiguro, Yukio,Furukawa, Shoei
, p. 1569 - 1572 (1994)
The structures of novel diterpenoids, erinacines A, B, and C, isolated from the cultured mycelia of Hericium erinaceum were determined by interpretation of the spectral data, and chemical and enzymatic reactions. These compounds showed potent stimulating activity of nerve growth factor (NGF)-synthesis
Isolation of erinacine P, a new parental metabolite of cyathane- xylosides, from Hericium erinaceum and its biomimetic conversion into erinacines A and B
Kenmoku, Hiromichi,Sassa, Takeshi,Kato, Nobuo
, p. 4389 - 4393 (2000)
A new cyathane-xyloside, erinacine P, was isolated from mycelia of basidiomycetous Hericium erinaceum YB4-6237 in a shaken culture. Since its aglycon closely resembles typical cyathane diterpenoids such as cyathins and cyathatriols in its substitution pattern, this glycoside seems to be an important metabolite in the biosynthesis of erinacines and striatins. In fact, according to our biogenesis studies, erinacine P can be successfully converted chemically into erinacine B and, further, to erinacine A under mild conditions. (C) 2000 Elsevier Science Ltd.
Enantioselective total synthesis of (-)-erinacine B
Watanabe, Hideaki,Takano, Masashi,Umino, Akinori,Ito, Toshiya,Ishikawa, Hiroyuki,Nakada, Masahisa
, p. 359 - 362 (2007/10/03)
(Chemical Equation Presented) The first enantioselective total synthesis of (-)-erinacine B has been achieved. Our approach features convergent construction of the 5-6-7 tricyclic cyathane core system via chiral building blocks prepared using asymmetric c
