156127-34-3 Usage
Uses
Used in Pharmaceutical Industry:
6,10-Methanobenzocyclodecene-3,5,7,11-tetrol,1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-9,12a,13,13-tetramethyl-4-methylene-,3,5,7,11-tetraacetate, (3S,4aS,5S,6S,7S,11S,12aS)is used as a pharmaceutical compound for its potential therapeutic properties. The presence of multiple hydroxyl and methyl groups, along with the specific stereochemistry, may contribute to its interaction with biological targets and its efficacy in treating certain conditions.
Used in Chemical Synthesis:
In the chemical synthesis industry, 6,10-Methanobenzocyclodecene-3,5,7,11-tetrol,1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-9,12a,13,13-tetramethyl-4-methylene-,3,5,7,11-tetraacetate, (3S,4aS,5S,6S,7S,11S,12aS)can be used as a building block or intermediate in the synthesis of more complex molecules. Its unique structure and functional groups may be utilized in the development of novel compounds with specific properties and applications.
Used in Material Science:
6,10-Methanobenzocyclodecene-3,5,7,11-tetrol,1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-9,12a,13,13-tetramethyl-4-methylene-,3,5,7,11-tetraacetate, (3S,4aS,5S,6S,7S,11S,12aS)may also find applications in material science, particularly in the development of new materials with unique properties. The molecule's structure and functional groups could be exploited to create materials with specific characteristics, such as improved stability, solubility, or reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 156127-34-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,1,2 and 7 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 156127-34:
(8*1)+(7*5)+(6*6)+(5*1)+(4*2)+(3*7)+(2*3)+(1*4)=123
123 % 10 = 3
So 156127-34-3 is a valid CAS Registry Number.
156127-34-3Relevant academic research and scientific papers
Cheng, Kedi,Fang, Weishuo,Yang, Yujun,Xu, Hong,Meng, Chao,Kong, Man,He, Wenyi,Fang, Qicheng
, p. 73 - 75 (1996)
Three C-14 oxygenated taxanes were isolated from Taxus yunnanensis cell cultures. Copyright
Purification and characterization of acetyl coenzyme A: 10- hydroxytaxane O-acetyltransferase from cell suspension cultures of Taxus chinensis
Menhard, Birgitta,Zenk, Meinhart H.
, p. 763 - 774 (2007/10/03)
An O-acetyltransferase that catalyzes the regiospecific acetylation of a range of taxanes possessing an unsubstituted 10-hydroxyl group was detected and purified to apparent electrophoretic homogeneity from a cytosolic fraction of Taxus chinensis cell cultures. The purification involved negative calcium phosphate adsorption, sephadex desalting, DEAE, AcA44 chromatography, HighQ, CHT II, HiTrap Blue, Phenylsepharose and Mimetic Green purification steps. The purified acetyltransferase was found to be a monomeric protein of 71 ± 1.5 kDa that is highly regio- and stereospecific towards the 10β- hydroxyl group of the taxane molecule and is also active towards 10- desacetylbaccatine III. The acetyltransferase reaction had a pH optimum of 9.0 with halfmaximal activities at pH 6.8 and 10.8, respectively. The temperature optimum was at 35°C and the isoelectric point at 5.6. The apparent K(m) values for 10-desacetyltaxuyunnanine C and acetyl CoA were 23 and 61 μM, respectively. The turnover rate for the enzyme using both substrates was 0.2 mol mol-1 of enzyme. The kinetic optimum was determined to be K(cat)/K(m) = 8.7 s-1 L M-1.
