156243-41-3Relevant articles and documents
Synthesis and mutagenicity of a new mutagen, 2-amino-1,7,9- trimethylimidazo-[4,5-g]quinoxaline, and its analog
Achiwa,Shiozawa,Nukaya,Terao
, p. 408 - 409 (2007/10/02)
A new mutagen, 2-amino-1,7,9-trimethylimidazo-[4,5-g]quinoxaline (1), isolated from beef extract, was synthesized from 3-fluoro-2-methylaniline via an intermediate, 2,8-dimethyl-7-methylaminoquinoxaline (7a). Its 2- methylanalog (2) was also synthesized from the same intermediate. The synthetic 1 showed the same mutagenic activity as the isolated mutagen. However, 2 was non-mutagenic.