1562665-61-5

Basic information

• Product Name: 2-{[1-(3,5-dimethylbenzyl)-1H-benzimidazol-2-yl]sulfanyl}-N-[2-chloro-4-(methylsulfonyl)phenyl]acetamide
• Synonyms: 2-{[1-(3,5-dimethylbenzyl)-1H-benzimidazol-2-yl]sulfanyl}-N-[2-chloro-4-(methylsulfonyl)phenyl]acetamide
• CAS NO: 1562665-61-5
• Molecular Weight: 514.069
• Mol File: 1562665-61-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{[1-(3,5-dimethylbenzyl)-1H-benzimidazol-2-yl]sulfanyl}-N-[2-chloro-4-(methylsulfonyl)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[1-(3,5-dimethylbenzyl)-1H-benzimidazol-2-yl]sulfanyl}-N-[2-chloro-4-(methylsulfonyl)phenyl]acetamide(1562665-61-5)
• EPA Substance Registry System: 2-{[1-(3,5-dimethylbenzyl)-1H-benzimidazol-2-yl]sulfanyl}-N-[2-chloro-4-(methylsulfonyl)phenyl]acetamide(1562665-61-5)

Safety Data

• Hazardous Substances Data: 1562665-61-5(Hazardous Substances Data)

Upstream product

• 1285429-13-1 N-(3,5-dimethylbenzyl)-2-nitroaniline 
• 1562664-70-3 1-(3,5-dimethylbenzyl)-1,3-dihydro-2H-benzo[d]imidazole-2-thione 
• 1562667-03-1 2-chloro-N-[2-chloro-4-(methylsulfonyl)phenyl]acetamide 
• 1562666-50-5 2-amino-1-(3,5-dimethylbenzyl)aniline 
• 13244-35-4 2-chloro-4-(methylsulfonyl)aniline 
• 27129-86-8 1-bromomethyl-3,5-dimethylbenzene 
• 88-74-4 2-nitro-aniline 

Relevant articles and documents

Design and synthesis of N1-aryl-benzimidazoles 2-substituted as novel HIV-1 non-nucleoside reverse transcriptase inhibitors

A series of novel N1-aryl-2-arylthioacetamido-benzimidazoles were synthesized and evaluated as inhibitors of human immunodeficiency virus type-1 (HIV-1). Some of them proved to be effective in inhibiting HIV-1 replication at submicromolar and nanomolar concentration acting as HIV-1 non-nucleoside RT inhibitors (NNRTIs), with low cytotoxicity. The preliminary structure-activity relationship (SAR) of these new derivatives was discussed and rationalized by docking studies.