156274-30-5Relevant academic research and scientific papers
Expanding the scaffold for bacterial RNA polymerase inhibitors: Design, synthesis and structure-activity relationships of ureido-heterocyclic-carboxylic acids
Elgaher, Walid A. M.,Fruth, Martina,Groh, Matthias,Haupenthal, Joerg,Hartmann, Rolf W.
, p. 2177 - 2194 (2014/01/06)
The emergence of bacterial resistance requires the development of new antibiotics with an alternative mode of action. Based on class I, developed in our previous study, a new series of RNA polymerase (RNAP) inhibitors targeting the switch region was desig
Synthesis of thieno[3,2-d]pyrimidine-2,4-diones cyclic and acyclic nucleosides as potential anti HIV agents
Jourdan,Laduree,Robba
, p. 305 - 312 (2007/10/02)
Synthesis of cyclic and acyclic nucleosides was achieved by alkylation of 7-methyl or arylthieno[3,2-d]pyrimidine-2,4-diones following the Vorbruggen and Niedballa's method [1]. After a possible deprotection, potential anti HIV agents were obtained.
