156293-25-3Relevant academic research and scientific papers
Novel antifungal β-amino acids: Synthesis and activity against Candida albicans
Mittendorf, Joachim,Kunisch, Franz,Matzke, Michael,Militzer, Hans-Christian,Schmidt, Axel,Schoenfeld, Wolfgang
, p. 433 - 436 (2007/10/03)
A series of novel β-amino acids has been synthesized and tested for their in vitro antifungal activity against Candida albicans. A steep SAR was observed. β-Amino acid 21 (BAY 10-8888/PLD-118) revealed the most favourable activity-tolerability profile and was selected for clinical studies as a novel antifungal for the oral treatment of yeast infections.
Cyclopentane- and -pentene-β-amino acids
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, (2008/06/13)
The invention relates to cyclopentane- and -pentene-β-amino acids, processes for their preparation and their use as medicaments.
