1563174-75-3Relevant academic research and scientific papers
Reactions of vinyl sulfone with α-diazo-β-ketosulfone and Bestmann-Ohira reagent for the regioselective synthesis of highly functionalized pyrazoles
Kumar, Rahul,Nair, Deepa,Namboothiri, Irishi N.N.
, p. 1794 - 1799 (2014/03/21)
The 1,3-dipolar cycloaddition of diazomethylsulfone anion, generated in situ from α-diazo-β-ketosulfone, with vinyl sulfone proceeds in a regioselective manner to provide sulfonylpyrazoles. Similar reaction of diazomethylphosphonate anion, derived from Bestmann-Ohira reagent, with vinyl sulfone leads to phosphonylpyrazoles. The sulfonyl group of vinyl sulfone undergoes chemoselective elimination in these reactions.
