156325-05-2

Upstream product

• 103-71-9 phenyl isocyanate 
• 156325-04-1 [(R)-((2S,3R)-3-Hydroxymethyl-oxiranyl)-(4-methoxy-phenyl)-methyl]-carbamic acid tert-butyl ester 
• 27460-85-1 N-(tert-butoxycarbonyl)-D-(4-hydroxyphenyl)glycine 
• 850166-76-6 (R)-(1-(4-methoxyphenyl)-2-oxoethyl) tert-butyl carbamate 
• 156325-03-0 [(Z)-(S)-4-Hydroxy-1-(4-methoxy-phenyl)-but-2-enyl]-carbamic acid tert-butyl ester 
• 156324-98-0 [(R)-(Methoxy-methyl-carbamoyl)-(4-methoxy-phenyl)-methyl]-carbamic acid tert-butyl ester 
• 156325-02-9 (Z)-(S)-4-tert-Butoxycarbonylamino-4-(4-methoxy-phenyl)-but-2-enoic acid methyl ester 

Downstream Products

• 156324-96-8 Acetic acid (1S,2S)-2,3-diacetoxy-1-[(R)-tert-butoxycarbonylamino-(4-methoxy-phenyl)-methyl]-propyl ester 
• 156407-79-3 [(1R,2S,3S)-2,3,4-Trihydroxy-1-(4-methoxy-phenyl)-butyl]-carbamic acid tert-butyl ester 
• 156325-06-3 [(1R,2S)-2-Hydroxy-1-(4-methoxy-phenyl)-2-((S)-2-oxo-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

An Efficient Synthesis of Polyoxamic Acid Utilizing the Aryl Group as the Carboxyl Synthon. A New Approach to Polyhydroxyamino Acids.

Polyoxamic acid (1), an amino acid moiety of antifungal antibiotics polyoxins, has been efficiently synthesized from Boc-(R)-4-hydroxyphenylglycine (3) utilizing its aryl group as the carbonyl synthon.