156326-76-0

Upstream product

• 156326-68-0 (S)-1-Ethyl-2-<(trimethylsilyl)oxy>-2-cyclohexene-1-propanoic acid methyl ester 
• 115867-85-1 (+)-(S)-1-Ethyl-2-oxocyclohexane-1-propanoic acid methyl ester 
• 156326-69-1 (+)-(S)-1-Ethyl-2-oxo-3-cyclohexene-1-propanoic acid methyl ester 
• 108-98-5 thiophenol 

Downstream Products

• 1067884-95-0 (+)-(S)-1-Ethyl-2-oxo-4-methoxy-3-cyclohexene-1-propanoic acid methyl ester 
• 7013-58-3 (+)-aspidospermidine 
• 156326-78-2 (+)-(S)-1-Ethyl-2,4-dioxocyclohexane-1-propanoic acid methyl ester 
• 156326-79-3 (+)-(S)-1-Ethyl-2-oxo-4-<(2-iodophenyl)amino>-3-cyclohexene-1-propanoic acid methyl ester 
• 156326-82-8 (R)-4a-Ethyl-2,3,4,4a,5,6-hexahydro-7-<(4-methoxyphenyl)sulfonyl>-7H-pyrido<3,2-c>carbazole 
• 1026461-33-5 (R)-3-(3-Amino-propyl)-3-ethyl-9-(4-methoxy-benzenesulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-4-ol 
• 156326-89-5 (+)-2,3-Didehydro-1-<(4-methoxyphenyl)sulfonyl>aspidospermidin-10-one 
• 156326-81-7 (+)-(R)-3-(3-Azidopropyl)-3-ethyl-9-<(4-methoxyphenyl)sulfonyl>-1,2,3,9-tetrahydro-4H-carbazol-4-one 
• 156408-07-0 (+)-(4aR,11cS)-4a-Ethyl-1-<(phenylthio)acetyl>-cis-2,3,4,4a,5,6,7,11c-octahydro-7-<(4-methoxyphenyl)sulfonyl>-1H-pyrido<3,2-c>carbazole 

Relevant academic research and scientific papers

Stereocontrolled Elaboration of Quaternary Carbon Centers through the Asymmetric Michael Reaction Using Chiral Imines: Enantioselective Synthesis of (+)-Aspidospermidine

An enantioselective synthesis of (+)-aspidospermidine (1b) has been developed.The key strategic element was the stereocontrolled elaboration of quaternary carbon centers through the asymmetric Michael reaction, using chiral imines under neutral conditions