156426-51-6Relevant articles and documents
Synthesis and testing of heterocyclic analogues of diaminopimelic acid (DAP) as inhibitors of DAP dehydrogenase and DAP epimerase
Abbott, Shaun D.,Lane-Bell, Patricia,Sidhu, Kanwar P. S.,Vederas, John C.
, p. 6513 - 6520 (2007/10/02)
Substrate analogues were synthesized and examined as inhibitors of diaminopimelic acid (DAP) dehydrogenase from Bacillus sphaericus and of DAP epimerase from Escherichia coli. These enzymes produce meso-DAP (3) (a precursor for L-lysine and for peptidogly