156426-54-9Relevant academic research and scientific papers
Diaminopimelic acid (DAP) analogs bearing isoxazoline moiety as selective inhibitors against meso-diaminopimelate dehydrogenase (m-Ddh) from Porphyromonas gingivalis
Ma, Hongguang,Stone, Victoria N.,Wang, Huiqun,Kellogg, Glen E.,Xu, Ping,Zhang, Yan
, p. 3840 - 3844 (2017/07/27)
Two diastereomeric analogs (1 and 2) of diaminopimelic acid (DAP) bearing an isoxazoline moiety were synthesized and evaluated for their inhibitory activities against meso-diaminopimelate dehydrogenase (m-Ddh) from the periodontal pathogen, Porphyromonas
Synthesis and testing of heterocyclic analogues of diaminopimelic acid (DAP) as inhibitors of DAP dehydrogenase and DAP epimerase
Abbott, Shaun D.,Lane-Bell, Patricia,Sidhu, Kanwar P. S.,Vederas, John C.
, p. 6513 - 6520 (2007/10/02)
Substrate analogues were synthesized and examined as inhibitors of diaminopimelic acid (DAP) dehydrogenase from Bacillus sphaericus and of DAP epimerase from Escherichia coli. These enzymes produce meso-DAP (3) (a precursor for L-lysine and for peptidogly
