1564286-55-0

Basic information

• Product Name: (3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine
• Synonyms: (3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine;(3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl)amino]benzoyl]glycyl-3-[3-bromo-5-(1,1-dimethylethyl)phenyl]-beta-alanine;(2S)-2-(3-bromo-5-(tert-butyl)phenyl)-3-(2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzamido)acetamido)propanoic acid;(3S)-3-(3-Bromo-5-(tert-butyl)phenyl)-3-(2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidi
• CAS NO: 1564286-55-0
• Molecular Formula: C₂₆H₃₂BrN₅O₆
• Molecular Weight: 590.46618
• EINECS: -0
• Mol File: 1564286-55-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.52±0.1 g/cm3(Predicted)
• PKA: 4.10±0.10(Predicted)
• CAS DataBase Reference: (3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine(1564286-55-0)
• EPA Substance Registry System: (3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine(1564286-55-0)

Safety Data

• Hazardous Substances Data: 1564286-55-0(Hazardous Substances Data)

Usage

Description

(3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine is a complex organic compound with a unique molecular structure. It is characterized by its hydroxy and amino groups, which allow for interactions with various biopolymers and macromolecules. (3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine has potential applications in various fields due to its structural properties and ability to modulate specific biological processes.

Uses

Used in Pharmaceutical Industry:
(3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine is used as a pharmaceutical candidate for the development of new drugs. Its unique molecular structure and functional groups enable it to interact with specific biological targets, making it a promising candidate for the treatment of various diseases.
Used in Drug Delivery Systems:
In the field of drug delivery, (3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine can be used as a component in the design of novel drug delivery systems. Its ability to interact with biopolymers and macromolecules can be exploited to improve the delivery, bioavailability, and therapeutic outcomes of various drugs.
Used in Research and Development:
(3S)-N-[3-Hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyriMidinyl)aMino] benzoyl]glycyl-3-(3-broMo-5-t-butylphenyl)-beta-alanine can also be used in research and development for the study of cell adhesion, migration, growth, and differentiation. Its potential to modulate specific biological processes makes it a valuable tool for understanding the underlying mechanisms of various diseases and for the development of targeted therapies.

Upstream product

• 1564286-57-2 (3S)-N-[3-hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl)amino]benzoyl]glycyl-3-(3-bromo-5-tert-butylphenyl)-β-alanine ethyl ester 
• 1541197-69-6 (S)-3-amino-3-(3-bromo-5-tert-butylphenyl)propionic acid 
• 1541197-67-4 3-amino-3-(3-bromo-5-tert-butylphenyl)propionic acid ethyl ester hydrochloride salt 
• 129316-09-2 1,3-dibromo-5-t-butylbenzene 
• 1541197-48-1 C₁₅H₂₀N₄O₅ 
• 240431-49-6 3-hydroxy-5-[(5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino]benzoic acid 
• 290826-72-1 2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzamido)acetic acid 
• 1541197-65-2 3-amino-3-(3-bromo-5-tert-butylphenyl)propionic acid 
• 241155-85-1 3-bromo-5-formyl-tert-butylbenzene 

Relevant articles and documents

3,5 Phenyl-Substituted Beta Amino Acid Derivatives as Integrin Antagonists

Disclosed herein are novel pharmaceutical agents which are useful as integrin receptor antagonists that mediate the pathologic processes of angiogenesis and fibrosis and as such are useful in pharmaceutical compositions and in methods for treating conditions mediated by these integrins by inhibiting or antagonizing these integrins. The novel pharmaceutical agents include those of the formula: wherein X is bromo or iodo, or pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods and intermediates useful for making the pharmaceutical agents and methods of using the pharmaceutical agents are also provided.