156448-08-7Relevant academic research and scientific papers
Synthesis and self-assembly of DNA-chromophore hybrid amphiphiles
Albert, Shine K.,Golla, Murali,Thelu, Hari Veera Prasad,Krishnan, Nithiyanandan,Deepak, Perapaka,Varghese, Reji
, p. 6960 - 6969 (2016)
DNA based spherical nanostructures are one of the promising nanostructures for several biomedical and biotechnological applications due to their excellent biocompatibility and DNA-directed surface addressability. Herein, we report the synthesis and amphiphilicity-driven self-assembly of two classes of DNA (hydrophilic)-chromophore (hydrophobic) hybrid amphiphiles into spherical nanostructures. A solid-phase "click" chemistry based modular approach is demonstrated for the synthesis of DNA-chromophore amphiphiles. Various spectroscopic and microscopic analyses reveal the self-assembly of the amphiphiles into vesicular and micellar assemblies with the corona made of hydrophilic DNA and the hydrophobic chromophoric unit as the core of the spherical nanostructures.
Self-assembly and phase separation of amphiphilic dyads based on 4,7-bis(2-thienyl)benzothiodiazole and perylene diimide
Peng, Jiang,Zhai, Feng,Guo, Xinyan,Jiang, Xinpeng,Ma, Yuguo
, p. 13078 - 13084 (2014/04/03)
To get highly ordered organic structures at the nanoscale, a series of new electronic donor-acceptor (D-A) dyads were synthesized. The dyads bearing different side chains (lipophilic or amphiphilic) or linkers (Long or Short) showed variable self-assembly behaviour. Long-linker dyads can fold in dilute solution, but the folding of short-linker dyads was not observed. Intermolecular D-A interactions and acceptor-acceptor (A-A) aggregation were proved to co-occur in chloroform for all four dyads. In the bulk state, amphiphilic dyads could overcome the intrinsic D-A interactions and achieve better D-A phase separation than lipophilic ones due to the incompatibility of the side chains. The dyad with a short-linker and amphiphilic side chains, Samphi, had the ability to form a gel, and both of the amphiphilic dyads could form nanofibres. This journal is the Partner Organisations 2014.
