156454-75-0Relevant articles and documents
Synthesis and anticancer activity of 2-substituted 2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one and its 2-oxide derivatives
Kostka,Porada,Graczyk
, p. 233 - 236 (2007/10/02)
As a result of the reaction of salicylic amide with PCl3 and POCl3 2-chloro-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one (1) and its 2-oxide 2 are obtained. Compounds 1 and 2 form amides with amines in 2-position. Antineoplastic action of the derivatives containing the bis(2-chloroethyl)amide group in 2-position was found.