156469-70-4 Usage
General Description
4-Phenylpyrrolidine-3-methylcarboxylate is a chemical compound with a molecular formula of C13H17NO2. 4-PHENYLPYRROLIDINE-3-METHYLCARBOXYLATE belongs to the class of organic compounds known as phenylpyrrolidines, which are polycyclic aromatic compounds containing a benzene ring linked to a pyrrolidine ring through a C=C bond. As a synthetic compound, it is largely used as an intermediate in the production of various pharmaceutical and cosmetic products. Not much is known about its environmental impact or toxicity, therefore, proper handling with adequate safety measures is advised.
Check Digit Verification of cas no
The CAS Registry Mumber 156469-70-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,4,6 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 156469-70:
(8*1)+(7*5)+(6*6)+(5*4)+(4*6)+(3*9)+(2*7)+(1*0)=164
164 % 10 = 4
So 156469-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO2/c1-15-12(14)11-8-13-7-10(11)9-5-3-2-4-6-9/h2-6,10-11,13H,7-8H2,1H3/t10-,11+/m0/s1
156469-70-4Relevant articles and documents
Pyrrolidine-carboxamides and oxadiazoles as potent hNK1 antagonists
Young, Jonathan R.,Eid, Ronsar,Turner, Cherilyn,DeVita, Robert J.,Kurtz, Marc M.,Tsao, Kwei-Lan C.,Chicchi, Gary G.,Wheeldon, Alan,Carlson, Emma,Mills, Sander G.
, p. 5310 - 5315 (2008/03/11)
The preparation and structure-activity-relationships of novel pyrrolidine-carboxamides and oxadiazoles are described. Compounds in this series were found to be potent hNK1 antagonists in vitro and efficacious in vivo with minimal interactions with P450 liver enzymes. Oxadiazole analog 22 was determined to have excellent hNK1 binding affinity, functional activity, and a good PD response in vivo.
