156469-70-4 Usage
Uses
Used in Pharmaceutical Industry:
4-Phenylpyrrolidine-3-methylcarboxylate is used as a chemical intermediate for the synthesis of various pharmaceutical products. Its unique structure allows it to be a key component in the development of new drugs, potentially contributing to the treatment of various medical conditions.
Used in Cosmetic Industry:
In the cosmetic industry, 4-Phenylpyrrolidine-3-methylcarboxylate is utilized as a raw material in the formulation of cosmetic products. Its presence in these products may be attributed to its ability to enhance the performance or stability of the final formulation, ensuring a better user experience and product efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 156469-70-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,4,6 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 156469-70:
(8*1)+(7*5)+(6*6)+(5*4)+(4*6)+(3*9)+(2*7)+(1*0)=164
164 % 10 = 4
So 156469-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO2/c1-15-12(14)11-8-13-7-10(11)9-5-3-2-4-6-9/h2-6,10-11,13H,7-8H2,1H3/t10-,11+/m0/s1
156469-70-4Relevant articles and documents
Pyrrolidine-carboxamides and oxadiazoles as potent hNK1 antagonists
Young, Jonathan R.,Eid, Ronsar,Turner, Cherilyn,DeVita, Robert J.,Kurtz, Marc M.,Tsao, Kwei-Lan C.,Chicchi, Gary G.,Wheeldon, Alan,Carlson, Emma,Mills, Sander G.
, p. 5310 - 5315 (2008/03/11)
The preparation and structure-activity-relationships of novel pyrrolidine-carboxamides and oxadiazoles are described. Compounds in this series were found to be potent hNK1 antagonists in vitro and efficacious in vivo with minimal interactions with P450 liver enzymes. Oxadiazole analog 22 was determined to have excellent hNK1 binding affinity, functional activity, and a good PD response in vivo.
