15647-11-7Relevant articles and documents
PROCESS FOR PREPARING ISOPHORONE AMINO ALCOHOL (IPAA)
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Paragraph 0056; 0057; 0058, (2018/08/30)
The present invention relates to an improved process for preparing 3-(aminomethyl)-3,5,5-trimethylcyclohexanol, called isophorone amino alcohol (IPAA) hereinafter. In particular, the present invention is directed to a one-stage process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexanol by hydrogenation of isophoronenitrile (IPN) with hydrogen over a catalyst, in the presence or absence of solvents, wherein the catalyst has certain properties.
COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA
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, (2011/09/14)
A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R4 and Ar are as defined in description and in claims, can be used as a medicament.
A new route for the convenient synthesis of 3-aminomethyl-3,5,5-trimethyl- cyclohexanol
Pandey, Satish C.,Singh, Sudhir S.,Patro, Balaram,Ghosh, Anil C.
, p. 2705 - 2707 (2007/10/03)
There has been a considerable chemical and biological interest in influenza fusion inhibitors namely, 3-aminomethyl-3,5,5-trimethyl-cyclohexanol 5. This compound has been identified as an important inhibitor of influenza virus fusion derivative and a potent and effective surrogate for the quinolizidine moiety. A new convenient route for the synthesis of 5 and for two new intermediates 1,3,3-trimethyl-5-oxo-cyclohexane-carboxylic acid amide 3 and 5-hydroxy-1,3,3-trimethyl-cyclohexane-carboxylic acid amide 4.