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156516-22-2

(3R,6S)-6-((S)-3-Benzyloxy-2-methoxy-propyl)-3-methyl-tetrahydro-pyran-2-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 156516-22-2 Structure

  • Basic information

    1. Product Name: (3R,6S)-6-((S)-3-Benzyloxy-2-methoxy-propyl)-3-methyl-tetrahydro-pyran-2-one
    2. Synonyms: (3R,6S)-6-((S)-3-Benzyloxy-2-methoxy-propyl)-3-methyl-tetrahydro-pyran-2-one
    3. CAS NO:156516-22-2
    4. Molecular Formula:
    5. Molecular Weight: 292.375
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 156516-22-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (3R,6S)-6-((S)-3-Benzyloxy-2-methoxy-propyl)-3-methyl-tetrahydro-pyran-2-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: (3R,6S)-6-((S)-3-Benzyloxy-2-methoxy-propyl)-3-methyl-tetrahydro-pyran-2-one(156516-22-2)
    11. EPA Substance Registry System: (3R,6S)-6-((S)-3-Benzyloxy-2-methoxy-propyl)-3-methyl-tetrahydro-pyran-2-one(156516-22-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 156516-22-2(Hazardous Substances Data)

156516-22-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 156516-22-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,5,1 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 156516-22:
(8*1)+(7*5)+(6*6)+(5*5)+(4*1)+(3*6)+(2*2)+(1*2)=132
132 % 10 = 2
So 156516-22-2 is a valid CAS Registry Number.

156516-22-2Relevant articles and documents

Total Synthesis of rapamycin

Ley, Steven V.,Tackett, Miles N.,Maddess, Matthew L.,Anderson, James C.,Brennan, Paul E.,Cappi, Michael W.,Heer, Jag P.,Helgen, Celine,Kori, Masakuni,Kouklovsky, Cyrille,Marsden, Stephen P.,Norman, Joanne,Osborn, David P.,Palomero, Maria A.,Pavey, John B. J.,Pinel, Catherine,Robinson, Lesley A.,Schnaubelt, Juergen,Scott, James S.,Spilling, Christopher D.,Watanabe, Hidenori,Wesson, Kieron E.,Willis, Michael C.

experimental part, p. 2874 - 2914 (2009/12/25)

For over 30 years, rapamycin has generated a sustained and intense interest from the scientific community as a result of its exceptional pharmacological properties and challenging structural features. In addition to its well known therapeutic value as a potent immunosuppressive agent, rapamycin and its derivatives have recently gained prominence for the treatment of a wide variety of other human malignancies. Herein we disclose full details of our extensive investigation into the synthesis of rapamycin that culminated in a new and convergent preparation featuring a macro-etherification/catechol-templating strategy for construction of the macrocyclic core of this natural product.

Studies towards the total synthesis of rapamycin: Preparation of the C10-C17 carbon unit

Ley, Steven V.,Norman, Joanne,Pinel, Catherine

, p. 2095 - 2098 (2007/10/02)

The preparation of the C10 - C17 carbon unit of the immunosuppressive agent rapamycin is reported via two routes leading to the substituted lactone 4.

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