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2-[(1,1-DIMETHYLETHYL) AMINO]-1-[4-OH-3-(HYDROXYMETHYL)PHENYL]ETHAN-1-ONE, commonly known as Tapentadol, is a centrally-acting synthetic analgesic that possesses both opioid and non-opioid properties. It is specifically designed to treat moderate to severe acute or chronic pain in adults. Tapentadol operates by binding to the mu-opioid receptors in the central nervous system, which diminishes the perception of pain. Additionally, it inhibits the reuptake of norepinephrine, thereby enhancing its analgesic effects. Tapentadol is available in both immediate-release and extended-release formulations, and its use requires caution due to the potential for abuse and addiction. Side effects may include constipation, nausea, dizziness, and drowsiness, and it is contraindicated in patients with significant respiratory depression or gastrointestinal obstruction.

156547-62-5

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156547-62-5 Usage

Uses

Used in Pharmaceutical Industry:
Tapentadol is used as an analgesic agent for the management of moderate to severe acute or chronic pain in adults. Its dual mechanism of action, involving both opioid receptor binding and norepinephrine reuptake inhibition, makes it effective in reducing pain perception and enhancing pain relief.
Used in Pain Management:
As a centrally-acting analgesic, Tapentadol is utilized for pain management in various clinical settings, including postoperative pain, chronic pain conditions such as neuropathic pain, and cancer pain. Its extended-release formulation allows for sustained pain relief over an extended period, making it suitable for long-term pain management.
Used in Research and Development:
Tapentadol serves as a subject of interest in pharmaceutical research and development, particularly in the exploration of novel analgesic agents with reduced potential for abuse and addiction. Its unique mechanism of action provides insights into the development of new drugs that can offer effective pain relief while minimizing the risk of dependence and side effects.
Used in Drug Formulation Development:
In the field of drug formulation development, Tapentadol is used to create various dosage forms, such as immediate-release and extended-release tablets, to cater to different patient needs and preferences. The development of these formulations aims to optimize the drug's pharmacokinetics, bioavailability, and therapeutic efficacy while minimizing adverse effects.

Check Digit Verification of cas no

The CAS Registry Mumber 156547-62-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,5,4 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 156547-62:
(8*1)+(7*5)+(6*6)+(5*5)+(4*4)+(3*7)+(2*6)+(1*2)=155
155 % 10 = 5
So 156547-62-5 is a valid CAS Registry Number.

156547-62-5 Well-known Company Product Price

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  • Sigma-Aldrich

  • (Y0001186)  Salbutamol impurity J  European Pharmacopoeia (EP) Reference Standard

  • 156547-62-5

  • Y0001186

  • 1,880.19CNY

  • Detail
  • USP

  • (1012655)  Albuterol Related Compound B  United States Pharmacopeia (USP) Reference Standard

  • 156547-62-5

  • 1012655-10MG

  • 14,500.98CNY

  • Detail

156547-62-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(tert-butylamino)-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanone

1.2 Other means of identification

Product number -
Other names 2-[(1,1-Dimethylethyl)amino]-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanone,Salbutamon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:156547-62-5 SDS

156547-62-5Upstream product

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