156574-94-6Relevant articles and documents
The semicarbazone peptidomimetic group in imino aza peptides
Limal,Limal, David,Grand,Grand, Vincent,Vanderesse,Vanderesse, Regis,Marraud,Marraud, Michel,Aubry,Aubry, Andre
, p. 3711 - 3714 (1994)
The semicarbazone moiety (C-CH=N-NR-CO-NH-C), either obtained by coupling a peptide aldehyde with a semicarbazide, or by action of an alkylisocyanate on a peptide hydrazone, is a dipeptide isostere. The structure of four amino aza dipeptides, analogues of the Pro-Gly, Pro-Ala and Pro-Phe dipeptides, has been studied in solution by 1H-NMR and IR spectroscopy, and in the solid state by X-ray diffraction.