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156579-01-0

dimethyl N-[[4-[(2,4-diaminopteridin-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl]-L-homoglutamate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 156579-01-0 Structure

  • Basic information

    1. Product Name: dimethyl N-[[4-[(2,4-diaminopteridin-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl]-L-homoglutamate
    2. Synonyms: dimethyl N-[[4-[(2,4-diaminopteridin-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl]-L-homoglutamate
    3. CAS NO:156579-01-0
    4. Molecular Formula:
    5. Molecular Weight: 540.603
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 156579-01-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: dimethyl N-[[4-[(2,4-diaminopteridin-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl]-L-homoglutamate(CAS DataBase Reference)
    10. NIST Chemistry Reference: dimethyl N-[[4-[(2,4-diaminopteridin-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl]-L-homoglutamate(156579-01-0)
    11. EPA Substance Registry System: dimethyl N-[[4-[(2,4-diaminopteridin-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl]-L-homoglutamate(156579-01-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 156579-01-0(Hazardous Substances Data)

156579-01-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 156579-01-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,5,7 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 156579-01:
(8*1)+(7*5)+(6*6)+(5*5)+(4*7)+(3*9)+(2*0)+(1*1)=160
160 % 10 = 0
So 156579-01-0 is a valid CAS Registry Number.

156579-01-0Downstream Products

156579-01-0Relevant articles and documents

An improved process for the large-scale preparation of antirheumatic agent MX-68

Maruyama, Noriaki,Shimizu, Hirohito,Sugiyama, Takashi,Watanabe, Masashi,Makino, Masashi,Kato, Masahiro,Shimizu, Makoto

, p. 883 - 888 (2004)

A large-scale preparation route of MX-68, a novel MTX derivative bearing a dihydro-2H-1,4-benzothiazine moiety and L-homogulutamic acid, is described. The original route that is a laboratory-scale synthesis for preclinical study has been improved. The improved process involves the following features: each step does not use haloalkane solvents, corrosive reagents, and chromatographic purification, and the formation of the major impurity at the final step is minimized. This improvement has enabled us to supply sufficient quantities of MX-68, which is required for both the toxicity test and the clinical study.

Synthesis of tritiated N-[4-(2,4-diaminopteridine-6-methyl)-3,4-dihydro-2H-1,4- benzothiazine-7-carbonyl]-L-homo glutamic acid (MX-68)

Matsuoka, Hiroharu,Kuroki, Toshio,Yano, Keiichi,Takeda, Yasuhisa

, p. 363 - 368 (2007/10/03)

Synthesis of tritiated N-[4-(2,4-diaminopteridine-6-methyl)-3,4-dihydro-2H-1,4-benzothiazine-7 -carbonyl]-L-homoglutamic acid, [9-3H,]MX-68 (3), is described. [9-3H1MX-68 (3) was prepared via tritiation at the carbonyl group in 2,4-bis(butanoylamino)-6-formylpteridine (7) with sodium borotritiide.

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