1565804-24-1Relevant articles and documents
A convergent synthesis of the fully elaborated macrocyclic core of TMC-95A
Coste, Alexis,Bayle, Alexandre,Marrot, Jerome,Evano, Gwilherm
, p. 1306 - 1309 (2014)
A concise and straightforward synthesis of the fully elaborated macrocyclic core of TMC-95A is reported. A highly efficient organocatalyzed aldolization between isatin and dihydroxyacetone derivatives and formation of the biaryl subunit with concomitant macrocyclization are the characteristic features of this synthesis.