1565852-63-2

Upstream product

• 41888-55-5 N-benzoyl-(4'-chloro)phenylalanine 
• 114820-38-1 Toluene-4-sulfonatephenyl-trimethylsilanylethynyl-iodonium; 
• 221071-22-3 4-(4-chloro-benzyl)-2-phenyl-4H-oxazol-5-one 

Relevant academic research and scientific papers

Alkynyliodonium salt mediated alkynylation of azlactones: Fast access to Cα-tetrasubstituted α-amino acid derivatives

An efficient electrophilic alkynylation of azlactones (oxazol-5(4H)-ones) is developed using alkynyl(phenyl)iodonium salts as the electrophilic alkyne source. After remarkably short reaction times, the desired alkyne functionalized azlactones are obtained in 60-97% yield and can be transformed easily into a variety of quaternary α-amino acid derivatives.