156589-82-1

Basic information

• Product Name: ETHYL 4-ISOPROPYLTHIAZOLE-2-CARBOXYLATE
• Synonyms: ETHYL 4-ISOPROPYLTHIAZOLE-2-CARBOXYLATE;Ethyl 4-isopropyl-thiazole-2-carboxylate, min. 95 %;2-Thiazolecarboxylic acid,4-(1-methylethyl)-,ethyl ester;Ethyl 4-isopropyl-2-thiazolecarboxylate;4-Isopropylthiazole-2-carboxylic acid ethyl ester;ethyl 4-propan-2-yl-1,3-thiazole-2-carboxylate
• CAS NO: 156589-82-1
• Molecular Formula: C₉H₁₃NO₂S
• Molecular Weight: 199.27
• Mol File: 156589-82-1.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 268℃
• Flash Point: 116℃
• Appearance: /
• Density: 1.128
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.516
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ETHYL 4-ISOPROPYLTHIAZOLE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-ISOPROPYLTHIAZOLE-2-CARBOXYLATE(156589-82-1)
• EPA Substance Registry System: ETHYL 4-ISOPROPYLTHIAZOLE-2-CARBOXYLATE(156589-82-1)

Safety Data

• Hazardous Substances Data: 156589-82-1(Hazardous Substances Data)

Usage

General Description

Ethyl 4-isopropylthiazole-2-carboxylate is a synthetic compound that falls under the category of thiazoles. These are aromatic compounds with a ring that is part of the larger group of azoles. Thiazoles are often used in developing pharmaceuticals, polymers, and other synthetic materials. Ethyl 4-isopropylthiazole-2-carboxylate, in particular, can be characterized by an ethyl group (carbon and hydrogen chains), a thiazole ring structure, and a carboxylate group. Information about its specific uses, safety, or toxicity might not be readily available and would likely require more specialized research or inquiries to chemical manufacturers or suppliers.

InChI:InChI=1/C9H13NO2S/c1-4-12-9(11)8-10-7(5-13-8)6(2)3/h5-6H,4H2,1-3H3

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Downstream Products

• 156589-83-2 (4-Isopropyl-1,3-thiazol-2-yl)methanol 
• 300831-06-5 4-isopropylthiazole-2-carboxylic acid 
• 923586-06-5 C₂₀H₂₆N₂O₃S 
• 300831-07-6 N-(2-acetyl-5-methoxyphenyl)-4-isopropylthiazole-2-carboxamide 
• 923289-59-2 4-isopropylthiazole-2-carbonyl chloride 
• 1108659-02-4 N-(3,5-dimethoxyphenyl)-4-isopropylthiazole-2-carboxamide 
• 1108659-05-7 N-(2-acetyl-3,5-dimethoxyphenyl)-4-isopropylthiazole-2-carboxamide 
• 1180495-76-4 methyl 3-chloro-2-(4-isopropylthiazole-2-carboxamido)-4-methoxybenzoate 
• 923274-69-5 4-Isopropylthiazole-2-carboxylic acid (6-carbamoyl-3-methoxy-2-methyl-phenyl)-amide 
• 923274-25-3 4-isopropylthiazole-2-carboxylic acid (2-carbamoyl-5-methoxy-phenyl)-amide 
• 923289-21-8 8-methyl-2-[4-(1-methylethyl)-1,3-thiazol-2-yl]-7-(methyloxy)-4-quinolinol 
• 923289-20-7 N-(6-acetyl-2-methyl-3-methoxyphenyl)-4-isopropylthiazole-2-carboxamide 
• 184154-42-5 4-isopropyl-1,3-thiazole-2-carbaldehyde 

Relevant articles and documents

2-(1H-INDOLE-3-CARBONYL)-THIAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS

2-(1H-lndole-3-carbonyl)-thiazole-4-carboxamide derivatives and the corresponding imidazole, oxazole and thiophene derivatives and related compounds as aryl hydrocarbon receptor (AHR) agonists for the treatment of angiogenesis implicated disorders, such as e.g. retinopathy, psoriasis, rheumatoid arthritis, obesity and cancer, or inflammatory disorders. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 27 to 32 and 59 to 219; examples 1 to 8; compounds 1-1 to 1-97; tables 1-a, 2 and 3).

Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections

Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, and pharmaceutical compositions and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.

ANTIMICROBIAL AGENTS

The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.