156604-66-9Relevant academic research and scientific papers
Quantitative assessment of the nature of noncovalent interactions in: N -substituted-5-(adamantan-1-yl)-1,3,4-thiadiazole-2-amines: Insights from crystallographic and QTAIM analysis
Al-Shaalan, Nora H.,Al-Wahaibi, Lamya H.,Blacque, Olivier,El-Awady, Mohamed I.,El-Emam, Ali A.,Janani, Krishnakumar,Percino, M. Judith,Saveeth Kumar, Elangovan,Thamotharan, Subbiah
, p. 9840 - 9853 (2020)
Three adamantane-1,3,4-thiadiazole hybrid derivatives namely; N-ethyl-5-(adamantan-1-yl)-1,3,4-thiadiazole-2-amine I, N-(4-fluorophenyl)-5-(adamantan-1-yl)-1,3,4-thiadiazole-2-amine II and (4-bromophenyl)-5-(adamantan-1-yl)-N-1,3,4-thiadiazole-2-amine III
Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-[3-(1-adamantyl)-4-substituted-5-thioxo-1,2,4-triazolin-1-yl]acetic acids, 2-[3-(1-adamantyl)-4-substituted-5-thioxo-1,2,4-triazolin-1-yl]propionic acids and related derivatives
Al-Deeb, Omar A.,Al-Omar, Mohamed A.,El-Brollosy, Nasser R.,Habib, Elsayed E.,Ibrahim, Tarek M.,El-Emam, Ali A.
, p. 40 - 47 (2007/10/03)
The reaction of 3-(1-adamantyl)-4-substituted-1,2,4-triazoline-5-thiones 3a-g with sodium chloroacetate, in ethanolic sodium hydroxide yielded the corresponding N1-acetic acid derivatives 4a g. The interaction of 3a-g with ethyl 2-bromopropiona
Adamantane Derivatives IV: Unexpected Debenzylation on Ring Closure of 1-(1-Adamantylcarbonyl)-4-benzylthiosemicarbazide with Sulphuric Acid
El-Emam, A. A.,Lehmann, J.
, p. 587 - 592 (2007/10/02)
Cyclization of 1-(1-adamantylcarbonyl)-4-substituted thiosemicarbazides 2a-e with sulphuric acid at ambient temperature or by heating with phosphorus oxychloride yielded the corresponding 2-(1-adamantyl)-5-amino-1,3,4-thiadiazoles 3a-e.Cyclization of 1-(1-adamantylcarbonyl)-4-benzylthiosemicarbazide 2f with sulphuric acid gave the debenzylated product 2-(1-adamantyl)-5-amino-1,3,4-thiadiazole 4.On the other hand, cyclization of 2f using phosphorus oxychloride yielded 2-(1-adamantyl)-5-benzylamino-1,3,4-thiadiazole 3f. - Keywords: Adamantanes; Debenzylation; 1,3,4-Thiadiazoles.
