156624-87-2

Basic information

• Product Name: (E)-(2S,3S)-3-Hydroxy-2,4-dimethyl-5-phenyl-pent-4-enethioic acid S-phenyl ester
• CAS NO: 156624-87-2
• Molecular Weight: 312.433
• Mol File: 156624-87-2.mol

Chemical Properties

• CAS DataBase Reference: (E)-(2S,3S)-3-Hydroxy-2,4-dimethyl-5-phenyl-pent-4-enethioic acid S-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(2S,3S)-3-Hydroxy-2,4-dimethyl-5-phenyl-pent-4-enethioic acid S-phenyl ester(156624-87-2)
• EPA Substance Registry System: (E)-(2S,3S)-3-Hydroxy-2,4-dimethyl-5-phenyl-pent-4-enethioic acid S-phenyl ester(156624-87-2)

Safety Data

• Hazardous Substances Data: 156624-87-2(Hazardous Substances Data)

Upstream product

• 18245-72-2 S-phenylthiopropionate 
• 15174-47-7 α-methyl-trans-cinnamaldehyde 

Downstream Products

• 156624-91-8 (4S,5S,6S)-5-Methyl-6-((E)-1-methyl-2-phenyl-vinyl)-4-triisopropylsilanyloxy-tetrahydro-pyran-2-one 
• 156624-88-3 tert-butyl (4S,5S,E)-5-hydroxy-4,6-dimethyl-3-oxo-7-phenylhept-6-enoate 
• 156624-89-4 tert-butyl (3S,4R,5S,E)-3,5-dihydroxy-4,6-dimethyl-7-phenylhept-6-enoate 
• 156624-90-7 (4S,5R,6S)-4-hydroxy-5-methyl-6-((E)-1-phenylprop-1-en-2-yl)tetrahydro-2H-pyran-2-one 

Relevant articles and documents

Total syntheses of close analogues of the immunosuppressant FK506

The total synthesis of an analogue of FK506, in which the substituted cyclohexyl residue at C28 has been replaced by a phenyl group, is described. This synthesis demonstrates (i) the successful application of new methodology for the introduction of the masked tricarbonyl grouping (C8-C10), and (ii) new synthetic routes to the (C10-C19) and (C22-C26) regions.