156641-12-2Relevant academic research and scientific papers
Diastereoselective oxidation of substituted 1,2-dithiolan-3-ones
Glass, Richard S.,Liu, Yunqi
, p. 3887 - 3888 (1994)
Oxidation of 1,2-dithiolan-3-ones 1 with one equivalent of dimethyldioxirane in dichloromethane at -78°C produces the corresponding 1,2-dithiolan-3-one 1-oxides 2 in high yields and with diastereoselectivities as high as 18:1. The major diastereomer formed is the trans isomer. An X-ray crystallographic structure study of the major diastereomer 2c obtained by oxidation of 1g is reported.
