1566418-37-8Relevant articles and documents
Direct transformation of arylpropynes to acrylamides via a three-step tandem reaction
Qiu, Jun,Zhang, Ronghua
, p. 1556 - 1560 (2014)
A novel and metal-free acrylamides formation between arylpropynes and hydroxylamine hydrochloride through sp3 C-H and C-C bond cleavage has been achieved with DDQ as an oxidant. The mechanistic study shows that the acrylamides are formed through a three-step tandem sequence, including cross-dehydrogenative-coupling (CDC) reaction, aza-Meyer-Schuster rearrangement and Beckmann rearrangement. This journal is The Royal Society of Chemistry 2014.