156721-25-4Relevant articles and documents
Asymmetric synthesis of unusual amino acids: Synthesis of optically pure isomers of N-indole-(2-mesitylenesulfonyl)-β-methyltryptophan
Boteju,Wegner,Qian,Hruby
, p. 2391 - 2404 (2007/10/02)
We have developed methods for the synthesis of the four optically pure isomers of β-methyltryptopham with the 2-mesitylenesulfonyl indole protecting group for peptide synthesis. Starting from 3-indoleacrylic acid, the β-methyl function was generated by a
Asymmetric synthesis of unusual amino acids: Synthesis of the optically pure isomers of indole-protected β-methyltryptophan suitable for peptide synthesis
Boteju,Wegner,Hruby
, p. 7491 - 7494 (2007/10/02)
The four isomers of N-indole-(2-mesitylenesulfonyl)-β-methyltryptophan have been synthesized in high optical purity using in part, asymmetric conjugate 1,4-additions followed by chiral imide enolate azidation and reduction.
