1567401-76-6Relevant articles and documents
Rapid generation of privileged substructure-based compound libraries with structural diversity and drug-likeness
Zhang, Lei,Zheng, Mingyue,Zhao, Fei,Zhai, Yun,Liu, Hong
, p. 184 - 191 (2014)
A library of privileged-substructure-based, heterocyclic compounds was constructed by a sequence of Ugi four-component reactions incorporating the indole motif and microwave-assisted cyclizations in branched pathways. Cheminformatic analysis confirmed that the library exhibited a high degree of structural diversity and good drug-likeness.