156769-33-4

Upstream product

• 156721-18-5 (3(2E), 4R)-3-<3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxopropenyl>-4-phenyl-2-oxazolidinone 
• 1204-06-4 trans-3-indole-acrylic acid 
• 90319-52-1 (4R)-phenyl-2-oxazolidinone 
• 1026568-43-3 C₂₅H₂₇NO₅S 
• 773-64-8 2-mesitylenesulphonyl chloride 
• 156721-22-1 (3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone 
• 156721-17-4 (2-mesitylenesulfonyl)indole-3-acrylic acid 

Downstream Products

• 156721-26-5 (2S, 3S)-2-azido-3-butanoic acid 

Relevant academic research and scientific papers

Asymmetric synthesis of unusual amino acids: Synthesis of optically pure isomers of N-indole-(2-mesitylenesulfonyl)-β-methyltryptophan

We have developed methods for the synthesis of the four optically pure isomers of β-methyltryptopham with the 2-mesitylenesulfonyl indole protecting group for peptide synthesis. Starting from 3-indoleacrylic acid, the β-methyl function was generated by a

Asymmetric synthesis of unusual amino acids: Synthesis of the optically pure isomers of indole-protected β-methyltryptophan suitable for peptide synthesis

The four isomers of N-indole-(2-mesitylenesulfonyl)-β-methyltryptophan have been synthesized in high optical purity using in part, asymmetric conjugate 1,4-additions followed by chiral imide enolate azidation and reduction.