156775-87-0Relevant academic research and scientific papers
Rotational features of carbon-nitrogen bonds in N-aryl maleimides. Atroposelective reactions of o-tert-butylphenylmaleimides
Curran, Dennis P.,Geib, Steven,DeMello, Nicholas
, p. 5681 - 5704 (2007/10/03)
Atroposelective addition and cycloaddition reactions of N-2- (tertbutylphenyl)- and N-2,5 (di-tert-butylphenyl)maleimide and a substituted derivative have been studied. Good to excellent stereoselectivities are generally observed, and high rotation barriers (about 29 kcal/mol) prevent the products from inter, converting. Crystal structures of the precursors and products support a straightforward model where reactants attack trans to the o-tert butyl group.
