156826-23-2Relevant academic research and scientific papers
Facile synthesis of a simplified bicyclo[7.3.1] esperamicin-calicheamicin enediyne core
Kadow, John F.,Cook, Donald J.,Doyle, Terrence W.,Langley, David R.,Pham, Kahnie M.,Vyas, Dolatrai M.,Wittman, Mark D.
, p. 1519 - 1538 (2007/10/02)
An efficient non cobalt mediated route for the synthesis of a simplified bicyclo[7.3.1]enediyne core of the naturally occurring calicheamicins and esperamicins is described. The key cyclization provides a single propargylic alcohol stereoisomer which is i
