156832-48-3

Upstream product

• 59531-24-7 2,3,4,6-tetra-O-benzyl-D-glucopyranoside 
• 156925-78-9 (2S)-1-O-(2,3,4,6-Tetra-O-benzyl-β-D-glucopyranosyl)-2,3-O-isopropylideneglycerol 

Downstream Products

• 156832-49-4 (2R)-1-O-(2,3,4,6-Tetra-O-benzyl-β-D-glucopyranosyl)-3-O-(tert-butyldimethylsilyl)glycerol 
• 156832-53-0 (2R)-1-O-(2,3,4,6-Tetra-O-benzyl-β-D-glucopyranosyl)-2-O-palmitoyl-3-O-<(2-bromoethoxy)benzoxyphosphoryl>glycerol 
• 156832-54-1 (2R)-1-O-(2,3,4,6-Tetra-O-benzyl-β-D-glucopyranosyl)-2-O-palmitoyl-3-O-phosphatidylcholinylglycerol 
• 156832-50-7 (2R)-1-O-(2,3,4,6-Tetra-O-benzyl-β-D-glucopyranosyl)-2-O-palmitoyl-3-O-(tert-butyldimethylsilyl)glycerol 
• 156832-51-8 (2S)-1-O-(2,3,4,6-Tetra-O-benzyl-β-D-glucopyranosyl)-2-O-palmitoylglycerol 

Relevant academic research and scientific papers

Synthesis of (2R)- and (2S)-β-D-glucopyranos-1-yl-2-O-palmitoyl-3-O-phosphatidylcholinylglyc erol: A new antifungal phosphocholine

The discovery of a new of antifungal agent, a glycosylated phosphatidylcholine, is reported, and the syntheses of the first two members of this series, (2S)-β-D-glucopyranos-1-yl-2-O-palmitoyl-3-O-phosphatidylcholinylglyc erol and (2R)-β-D-glucopyranos-1-yl-2-O-palmitoyl-3-O-phosphatidylcholinylglyc erol, are described. Their activities against the pathogenic fungi Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus are also reported.