1568990-34-0

Basic information

• Product Name: tert-butyl 6-chloro-1-tetralone-2-carboxylate
• Synonyms: tert-butyl 6-chloro-1-tetralone-2-carboxylate
• CAS NO: 1568990-34-0
• Molecular Weight: 280.751
• Mol File: 1568990-34-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 6-chloro-1-tetralone-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 6-chloro-1-tetralone-2-carboxylate(1568990-34-0)
• EPA Substance Registry System: tert-butyl 6-chloro-1-tetralone-2-carboxylate(1568990-34-0)

Safety Data

• Hazardous Substances Data: 1568990-34-0(Hazardous Substances Data)

Upstream product

• 26673-31-4 6-chloro-3,4-dihydronaphthalen-1(2H)-one 
• 49761-82-2 tert-butyl 1H-imidazole-1-carboxylate 

Relevant articles and documents

Asymmetric α-hydroxylation of tetralone-derived β-ketoesters by using a guanidine-urea bifunctional organocatalyst in the presence of cumene hydroperoxide

Highly enantioselective catalytic oxidation of 1-tetralone-derived β-keto esters was achieved by using a guanidine-urea bifunctional organocatalyst in the presence of cumene hydroperoxide (CHP), a safe, commercially available oxidant. The α-hydroxylation products were obtained in 99 % yield with up to 95 % enantiomeric excess (ee). The present oxidation was successfully applied to synthesize a key intermediate of the anti-cancer agent daunorubicin (2).