1569042-73-4

Basic information

• Product Name: (S)-2-amino-N-(((2S,5S,6R,7S,8R,10S)-8,10-diamino-6,7-dihydroxy-1-oxaspiro[4.5]decan-2-yl)methyl)-3-(1H-imidazol-5-yl)propanamide
• Synonyms: (S)-2-amino-N-(((2S,5S,6R,7S,8R,10S)-8,10-diamino-6,7-dihydroxy-1-oxaspiro[4.5]decan-2-yl)methyl)-3-(1H-imidazol-5-yl)propanamide
• CAS NO: 1569042-73-4
• Molecular Weight: 368.436
• Mol File: 1569042-73-4.mol

Chemical Properties

• CAS DataBase Reference: (S)-2-amino-N-(((2S,5S,6R,7S,8R,10S)-8,10-diamino-6,7-dihydroxy-1-oxaspiro[4.5]decan-2-yl)methyl)-3-(1H-imidazol-5-yl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-amino-N-(((2S,5S,6R,7S,8R,10S)-8,10-diamino-6,7-dihydroxy-1-oxaspiro[4.5]decan-2-yl)methyl)-3-(1H-imidazol-5-yl)propanamide(1569042-73-4)
• EPA Substance Registry System: (S)-2-amino-N-(((2S,5S,6R,7S,8R,10S)-8,10-diamino-6,7-dihydroxy-1-oxaspiro[4.5]decan-2-yl)methyl)-3-(1H-imidazol-5-yl)propanamide(1569042-73-4)

Safety Data

• Hazardous Substances Data: 1569042-73-4(Hazardous Substances Data)

Upstream product

• 17791-52-5 (S)-2-tert-Butoxycarbonylamino-3-(3H-imidazol-4-yl)-propionic acid 

Relevant articles and documents

Rigid spiroethers targeting the decoding center of the bacterial ribosome

Continuing our efforts towards understanding the principles governing ribosomal recognition and function, we have synthesized and evaluated a series of diversely functionalized 5,6-, 6,6- and 7,6-spiroethers. These compounds successfully mimic natural aminoglycosides regarding their binding to the decoding center of the bacterial ribosome. Their potential to inhibit prokaryotic protein production in vitro along with their antibacterial potencies have also been examined.