1569093-03-3Relevant academic research and scientific papers
Practical approach for asymmetric hydroxyamination of aldehydes with in situ generated nitrosocarbonyl compounds: Application to one-pot synthesis of chiral allylamines
Kano, Taichi,Shirozu, Fumitaka,Maruoka, Keiji
, p. 1530 - 1532 (2014/04/03)
The highly regio- and enantioselective hydroxyamination of aldehydes with in situ generated nitrosocarbonyl compounds from a hydroxamic acid derivative was realized by simple and readily available chiral amine catalysts. The resulting hydroxyamination products were readily converted to the corresponding chiral 1,2-aminoalcohol or allylamine derivatives in one pot.
