156912-05-9

Basic information

• Product Name: 3-amino-4-cyclohexylamino-1H-pyrazolo<4,3-c>quinoline
• CAS NO: 156912-05-9
• Molecular Weight: 281.36
• Mol File: 156912-05-9.mol

Chemical Properties

• CAS DataBase Reference: 3-amino-4-cyclohexylamino-1H-pyrazolo<4,3-c>quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-4-cyclohexylamino-1H-pyrazolo<4,3-c>quinoline(156912-05-9)
• EPA Substance Registry System: 3-amino-4-cyclohexylamino-1H-pyrazolo<4,3-c>quinoline(156912-05-9)

Safety Data

• Hazardous Substances Data: 156912-05-9(Hazardous Substances Data)

Upstream product

• 108-91-8 cyclohexylamine 
• 156912-01-5 3-amino-4-chloro-1H-pyrazolo<4,3-c>quinoline 
• 69875-54-3 2,4-Dichloroquinoline-3-carbonitrile 

Relevant articles and documents

Fused quinoline heterocycles. II. First synthesis of 1,2,3,4,5,6-hexaazaaceanthrylenes and 5,7,8,10a,11-pentaazabenzo[a]-fluorenes

The new tetracyclic ring systems 5-alkyl-1,5-dihydro-1,2,3,4,5,6-hexaazaaceanthrylenes 5a-d were synthesized by diazotization of 4-alkylamino-3-amino-1H-pyrazolo[4,3-c]quinolines 4a-d. The 4-arylamino-3-diazo-1H-pyrazolo-[4,3-c]quinolines 6e-h, which were prepared by diazotisation of the corresponding amines 4e-h, readily formed the novel tetracyclic ring system ethyl 6-arylamino-10-methyl-5,7,8,10a,11-pentaazabenzo[a]fluorene-9-carboxylates 8e-h, when treated with ethyl acetoacetate.

A convenient synthesis of new substituted pyrazolo[4,3-c]quinolines with potential antiinflammatory activity

2,4-Dichloro-quinoline-3-carbonitrile 1 reacts with hydrazines to afford pyrazolo[4,3-c]quinolines 5a, b. The reaction of 5a with sodium azide; hydrogen/Pd; triethylorthoformate; cyclohexylamine; piperidine; morpholine and acetic anhydride resulted in the corresponding heterocyclic derivatives 6-15.