156912-05-9Relevant articles and documents
Fused quinoline heterocycles. II. First synthesis of 1,2,3,4,5,6-hexaazaaceanthrylenes and 5,7,8,10a,11-pentaazabenzo[a]-fluorenes
Mekheimer
, p. 1971 - 1982 (2001)
The new tetracyclic ring systems 5-alkyl-1,5-dihydro-1,2,3,4,5,6-hexaazaaceanthrylenes 5a-d were synthesized by diazotization of 4-alkylamino-3-amino-1H-pyrazolo[4,3-c]quinolines 4a-d. The 4-arylamino-3-diazo-1H-pyrazolo-[4,3-c]quinolines 6e-h, which were prepared by diazotisation of the corresponding amines 4e-h, readily formed the novel tetracyclic ring system ethyl 6-arylamino-10-methyl-5,7,8,10a,11-pentaazabenzo[a]fluorene-9-carboxylates 8e-h, when treated with ethyl acetoacetate.
A convenient synthesis of new substituted pyrazolo[4,3-c]quinolines with potential antiinflammatory activity
Mekheimer
, p. 486 - 489 (2007/10/02)
2,4-Dichloro-quinoline-3-carbonitrile 1 reacts with hydrazines to afford pyrazolo[4,3-c]quinolines 5a, b. The reaction of 5a with sodium azide; hydrogen/Pd; triethylorthoformate; cyclohexylamine; piperidine; morpholine and acetic anhydride resulted in the corresponding heterocyclic derivatives 6-15.